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(Histone-H3)-lysine-36 demethylase
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(Histone-H3)-lysine-36 demethylase : ウィキペディア英語版
(Histone-H3)-lysine-36 demethylase

(Histone-H3)-lysine-36 demethylase (, ''JHDM1A'', ''JmjC domain-containing histone demethylase 1A'', ''H3-K36-specific demethylase'', ''histone-lysine (H3-K36) demethylase'', ''histone demethylase'', ''protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase'') is an enzyme with system name ''protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase''. This enzyme catalyses the following chemical reaction
: protein N6,N6-dimethyl-L-lysine + 2 2-oxoglutarate + 2 O2 \rightleftharpoons protein L-lysine + 2 succinate + 2 formaldehyde + 2 CO2 (overall reaction)
:(1a) protein N6,N6-dimethyl-L-lysine + 2-oxoglutarate + O2 \rightleftharpoons protein N6-methyl-L-lysine + succinate + formaldehyde + CO2
:(1b) protein N6-methyl-L-lysine + 2-oxoglutarate + O2 \rightleftharpoons protein L-lysine + succinate + formaldehyde + CO2
(Histone-H3)-lysine-36 demethylase contains iron(II).
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「(Histone-H3)-lysine-36 demethylase」の詳細全文を読む



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